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Arimoclomol maleate

产品编号:4116486
规格:≥98% (HPLC)
CAS NO:289893-26-1
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
411648610 MG968
411648650 MG3400
产品别名

289893-26-1

Arimoclomol maleate

BRX 220

maleate salt

N-[(2R)-2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidoyl chloride 1-oxide, maleate salt

(R)-3-(Chloro(2-hydroxy-3-(piperidin-1-yl)propoxyimino)methyl)pyridine 1-oxide, maleate salt

(+)-(R)-N-[2-Hydroxy-3-(1-piperidinyl)propoxy]pyridine-1-oxide-3-carboximidoyl chloride, maleate salt

BRX-220

Anti-neurodegeneration agent 1

BRX220

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H20ClN3O3 · C4H4O4
Molecular weight
429.85
MDL number
MFCD28143527
Biochem/physiol Actions【生化/生理作用】
Arimoclomol is an orally available, CNS-penetrant coinducer of heat shock proteins (HSPs), notably HSP70, that exhibits in vivo efficay in disease models of diabetes, Gaucher disease (GD), sporadic inclusion body myositis (sIBM), and neurological disorders, including amyotrophic lateral sclerosis (ALS) and Niemann-Pick disease type C1 (NPC1). Note: arimoclomol maleate and citrate salt forms are known as BRX-220 and BRX-345, respectively.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
H2O: 2 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
Cl/C(C1=CC=C[N+]([O-])=C1)=N\OC[C@@H](CN2CCCCC2)O.O=C(O)/C=C\C(O)=O
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