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Anti-WAS protein family homolog 1 (CT) Antibody
产品别名
Anti-WAS protein family homolog 1 (CT) Antibody
WAS protein family homolog 1, family with sequence similarity 39, member E, CXYorf1-like protein on chromosome 2, Protein FAM39E
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Wiskott-Aldrich Syndrome Protein and SCAR Homolog (WASH) is a novel protein belonging to the WASP family, a group of nucleation promoting factors (NFPs) that activate a critical component in endocytosis, Arp 2/3. WASH contains three specific domains: a C-terminal VCA domain, a proline-rich domain, and an N terminal region containing two WASH homolog regions, WHD1 and WHD2. Although WASH has yet to be completely characterized, it is known to function as an NPF at the endosomal surface, where it is involved in the recruitment and subsequent activation of Arp2/3 in order to initiate actin polymerization. Therefore, WASH has a crucial role in endosomal sorting as a mediator of tubule fission resulting from Arp2/3 activation. |
| Specificity【特异性】 | This antibody recognizes WAS protein family homolog 1 at the C-terminus. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus. Epitope: C-terminus |
| Application【应用】 | Anti-WAS protein family homolog 1 (C-terminus) Antibody detects level of WAS protein family homolog 1 (C-terminus) & has been published & validated for use in WB. Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected WAS protein family homolog 1 on 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NP_878908 |
| UniProt accession no.【UniProt登记号】 | A8K0Z3 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... WASH1(100287171) |
产品说明
| Target description【目标描述】 | ~ 60 kDa observed. The calculated molecular weight is 50 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
