Anti-Vimentin Antibody, clone LN-6

32160702

NA.41

Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.

Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.

Nuclei from adult human thymic biopsy specimens.

Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).

Liquid tissue culture supernatant containing 0.02% sodium azide.

Control
Hyperplastic lymph nodes.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

culture supernatant

primary antibodies

LN-6, monoclonal

human, mouse

Chemicon^®

immunohistochemistry: suitable (paraffin)

IgM

NM_003380.2

P08670

dry ice

human ... VIM(7431)

57-60 kDa

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11 - Combustible Solids

WGK 3