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Anti-Tryptophan hydroxylase 2 Antibody

产品编号:4115630
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4115630100 μG6350
产品别名

Anti-Tryptophan hydroxylase 2 Antibody

tryptophan hydroxylase 2, Tryptophan 5-monooxygenase 2, Neuronal tryptophan hydroxylase, tryptophan 5-hydroxylase 2

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Tryptophan hydroxylase 2 (TPH2) is preferentially expressed in the brain and is thought to play an important role in serotonin synthesis. Recent research has actually associated high levels of TPH2 with risk of suicide. Misfolding of TPH2 may be the cause of a loss of serotonin neuronal function in Parkinson’s disease. Detection and screening of particular mutations in TPH2 has been cited as an approach toward predicting patient sensitivity to potential antidepressant therapies and even the possibility of diagnosis of behavioral disorders.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to human Tryptophan hydroxylase 2.
Application【应用】
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience
Anti-Tryptophan hydroxylase 2 Antibody detects level of Tryptophan hydroxylase 2 & has been published & validated for use in WB, IH(P).
Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Tryptophan hydroxylase 2 in rat cerebral cortex tissue.
Quality【质量】
Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected Tryptophan hydroxylase 2 on 10 µg of rat brain tissue lysate.
Physical form【外形】
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Analysis Note【分析说明】
Control
Rat brain tissue lysate
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
human, rat
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_775567
UniProt accession no.【UniProt登记号】
Q8IWU9
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~56 kDa observed
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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