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Anti-TorsinA Antibody
基本信息
eCl@ss | 32160702 |
General description【一般描述】 | TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions. |
Specificity【特异性】 | TorsinA |
Immunogen【免疫原】 | Maltose binding protein fusion protein from human torsinA. |
Application【应用】 | Research Sub Category Developmental Neuroscience Neurodegenerative Diseases Research Category Neuroscience This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA. |
Physical form【外形】 | Ascites Liquid. Contaings no preservative |
Analysis Note【分析说明】 | Control Positive Control: Human brain lysate, NGF treated PC12 cells. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | ascites fluid |
antibody product type | primary antibodies |
clone【克隆】 | monoclonal |
species reactivity | human, mouse, rat |
manufacturer/tradename | Chemicon® |
technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1 |
NCBI accession no.【NCBI登记号】 | NM_000113.2 |
UniProt accession no.【UniProt登记号】 | O14656 |
shipped in【运输】 | dry ice |
Gene Information | human ... TOR1B(27348) |
产品说明
Target description【目标描述】 | 37kDa |
Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |