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Anti-SERPINB5 Antibody, clone 5C6.2
产品别名
Anti-SERPINB5 Antibody, clone 5C6.2
Serpin B5, SERPINB5, Maspin, Peptidase inhibitor 5, PI-5
基本信息
| eCl@ss | 32160702 |
| General description【一般描述】 | Serpin B5 (UniProt P36952; also known as Maspin, Peptidase inhibitor 5, PI-5) is encoded by the SERPINB5 (also known as PI5) gene (Gene ID 5268) in human. Serpin B5/Maspin is an evolutionarily conserved serine protease inhibitor that induces apoptosis and inhibits the motility of breast cancer cells. DNA hypermethylation and histone deacetylation lead to silencing of the SERPINB5 gene in human breast cancer. |
| Specificity【特异性】 | Does not detect spliced isoform 2 (UniProt P36952-2). |
| Immunogen【免疫原】 | Epitope: C-terminal half GST-tagged recombinant protein corresponding to the C-terminal of human SERPINB5. |
| Application【应用】 | Research Sub Category Apoptosis - Additional This Anti-SERPINB5 Antibody, clone 5C6.2 is validated for use in Western Blotting, Immunohistochemistry (Paraffin) for the detection of SERPINB5. Research Category Apoptosis & Cancer Western Blotting Analysis: 1.0 µg/mL from a representative lot detected SERPINB5 in 10 µg of HT-1080 and HT-29 cell lysates. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected SERPINB5 in human breast tissue. |
| Quality【质量】 | Evaluated by Western Blotting in HCT116 cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected SERPINB5 in 10 µg of HCT116 cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 5C6.2, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| isotype【同位素/亚型】 | IgG2bκ |
| NCBI accession no.【NCBI登记号】 | NP_002630 |
| UniProt accession no.【UniProt登记号】 | P36952 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... SERPINB5(5268) |
产品说明
| Target description【目标描述】 | ~42 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
