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Anti-PLK-4 Antibody

产品编号:4112906
规格:from rabbit
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4112906100 μG5850
产品别名

Anti-PLK-4 Antibody

Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase 18, Serine/threonine-protein kinase Sak

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Serine/threonine-protein kinase PLK4 (PLK-4) is a member of the protein kinase superfamily and plays an essential role in centriole duplication. PLK-4 triggers procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins. It may be involved in tumorigenesis since centrosome aberrations are frequently observed in tumors. PLK-4 may also be involved in trophoblast differentiation by phosphorylating HAND1, leading to the disruption between HAND1 and MDFIC and then activating HAND1.
Specificity【特异性】
This antibody recognizes the POLO box domain of PLK-4
Immunogen【免疫原】
Epitope: POLO box domain
KLH-conjugated linear peptide corresponding to the POLO box domain of human PLK-4.
Application【应用】
Research Category
Cell Structure
Anti-PLK-4 Antibody detects level of PLK-4 & has been published & validated for use in Western Blotting, ICC.
Research Sub Category
Cytoskeleton
Quality【质量】
Evaluated by Western Blot in Jurkat cell lysate.

Western Blot Analysis: 0.2 µg/mL of this antibody detected PLK-4 in 10 µg of Jurkat cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein A purified
Analysis Note【分析说明】
Control
Jurkat cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
mouse, rat, human
technique(s)
immunocytochemistry: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_0055079
UniProt accession no.【UniProt登记号】
O00444
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~95 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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