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Anti-Plexin-A3 Antibody, clone 18A9.2
产品别名
Anti-Plexin-A3 Antibody, clone 18A9.2
plexin A3, PLEXIN-A3, plexin-A3, Sex chromosome X transmembrane protein of HGF receptor family 3, Semaphorin receptor SEX, plexin-4, Plexin-4
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Plexin-A3 is a cell surface receptor for semaphorin that controls signaling for neuronal axon regulation. Plexin-A3 is thought to play a role in Sema3F and Sema3A signaling, has been described as essential for dorsal turning of the corticospinal tract axons and may be an important contributor to development of hippocampal axonal projections. Plexin-A3 has been found expressed in newly-differentiated sympathetic neurons, but not their neural crest precursors, and together with Plexin-A4, functions cooperatively to regulate the migration of sympathetic neurons and then differentially to guide the sympathetic axons. |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human Plexin-A3. |
Application【应用】 | Anti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC. Research Category Neuroscience Western Blot Analysis: 1 µg/mL from a previous lot detected Plexin-A3 on 10 µg of HT-29 and NIH/3T3 cell lysates. Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Plexin-A3 in colorectal carcinoma tissue. Research Sub Category Neurodegenerative Diseases |
Quality【质量】 | Evaluated by Western Blot in PC-12 cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Plexin-A3 on 10 µg of PC-12 cell lysate. |
Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G |
Analysis Note【分析说明】 | Control PC-12 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 18A9.2, monoclonal |
species reactivity | mouse, rat, human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_059984 |
UniProt accession no.【UniProt登记号】 | P51805 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~220 kDa observed. The calculated molecular weight of this protein is 208 kDa; however, a higher band may be observed due to glycosolation. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |