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Anti-Phospho-PLCG1-S1248 antibody produced in rabbit
产品别名
Anti-Phospho-PLCG1-S1248 antibody produced in rabbit
NCKAP3
PLC-II
PLC1
PLCG1
PLCgamma1
PLC148
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 148 |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | 1.08 mg/ml |
| technique(s) | immunohistochemistry: 1:10-1:100 western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | P19174 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PLCG1(5335) |
基本信息
| General description【一般描述】 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen【免疫原】 | A synthetic phosphorylated peptide around S1248 of human PLCG1 (NP_002651.2). |
| Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
| Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
