Anti-Phospho-PKC alpha-S657/Y658 antibody produced in rabbit

rabbit

100

primary antibodies

polyclonal

liquid

human, mouse

0.94 mg/mL

western blot: 1:500-1:2000

P17252

wet ice

−20℃

human ... PRKCA(5578)

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

A phospho specific peptide corresponding to residues surrounding S657/Y658 of human PKC alpha.

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.