广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-phospho-Peak Antibody (Tyr665)
产品搜索:

Anti-phospho-Peak Antibody (Tyr665)

产品编号:4112567
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4112567100 μG5420
产品别名

Anti-phospho-Peak Antibody (Tyr665)

Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Pseudopodium-enriched atypical kinase 1 (Peak1; KIAA2002, or sgk269) is a ubiquitous non-receptor tyrosine kinase that belongs to the NFK3 family. It interacts with actin filaments via its N-terminal actin-targeting region. It also modulates the activity of multiple cytoskeletal regulatory proteins such as paxillin, p130Cas, Erk, and Crk; and mediates cell proliferation and migration via the Ras/Raf/Erk and Src-p130Cas-Crk-Paxillin pathways. Peak1 may play an important role in the progression of tumors.
Specificity【特异性】
This antibody recognizes Peak phosphorylated at Tyr665.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to human Peak phosphorylated at Tyr665.
Epitope: Phosphorylated Tyr665
Application【应用】
Western Blot Analysis: A representative lot was used by an independent laboratory in 293T cells transfected with wildtype GFP-Peak. (Dr. Richard Klemke, University of California-San Diego.)
This phospho-Peak antibody is validated for use in WB & Dot Blot for the detection of the phospho-Peak protein.
Quality【质量】
Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins.

Dot Blot (Specificity) Analysis: A representative lot blocked phospho-Peak (Tyr665) in modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins.
Analysis Note【分析说明】
Affinity purified
Other Notes【其他说明】
Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Peak proteins
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), orangutan (Sumatran; based on 100% sequence homology), porcine (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
dot blot: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_079052
UniProt accession no.【UniProt登记号】
Q9H792
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
220 kDa calculated
【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0396