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Anti-Phospho-MCM2-S139 antibody produced in rabbit

产品编号:4112490
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41124905400
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
mouse, human, rat
concentration【浓度】
0.34 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P49736
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MCM2(4171)
基本信息
General description【一般描述】
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Immunogen【免疫原】
A synthetic phosphorylated peptide around S139 of human MCM2.
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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