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Anti-Phospho-LCP2-Y145 antibody produced in rabbit

产品编号:4112460
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4112460100 μL4710
产品别名

Anti-Phospho-LCP2-Y145 antibody produced in rabbit

SLP76

LCP2

SLP-76

产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
60
species reactivity
mouse, human
concentration【浓度】
2.42 mg/ml
technique(s)
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
Q13094
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... LCP2(3937)
基本信息
General description【一般描述】
SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Immunogen【免疫原】
A synthetic phosphorylated peptide around Y145 of human LCP2 (NP_005556.1).
Physical form【外形】
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品说明
Storage and Stability【储存及稳定性】
Store at -20℃. Avoid freeze / thaw cycles.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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