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Anti-Phospho-Erk1/2-T202/Y204 antibody produced in rabbit

产品编号:4112359
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41123594260
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
human, mouse, rat
concentration【浓度】
2.42 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P28482/P2736
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
基本信息
General description【一般描述】
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Immunogen【免疫原】
A phospho specific peptide corresponding to residues surrounding T202/Y204+T185/Y187 of human ERK1+ERK2.
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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