Anti-Phospho-ACLY-S455 antibody produced in rabbit

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

119
120
91

human, mouse, rat

1.15 mg/ml

immunohistochemistry: 1:50-1:100
immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000

P53396

wet ice

−20℃

human ... ACLY(47)

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

12 - Non Combustible Liquids

WGK 1