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Anti-Phospho-α-Synuclein-Y133 antibody produced in rabbit
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | liquid |
| species reactivity | mouse, human |
| concentration【浓度】 | 1.51 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | P37840 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SNCA(6622) |
基本信息
| General description【一般描述】 | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |
| Immunogen【免疫原】 | A phospho specific peptide corresponding to residues surrounding Y133 of human alpha-Synuclein. |
| Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
