Anti-PABPN1 antibody produced in rabbit

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

31
32
37

mouse, human

2.96 mg/ml

western blot: 1:500-1:1000

Q86U42

wet ice

−20℃

human ... PABPN1(8106)

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3′ ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5′ end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

12 - Non Combustible Liquids

WGK 1