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Anti-OCIAD1 Antibody
| 产品编号： | 4111643 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-OCIAD1 Antibody
OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | OCIA domain-containing protein 1, also known as Ovarian carcinoma immunoreactive antigen, and encoded by the gene name OCIAD1 or OCIA, was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients. expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; isoform 1 is highly expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland while isoform 2 is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid-(LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion |
| Immunogen【免疫原】 | KLH-conjugated synthetic peptide corresponding to the C-terminus of human OCIAD1. Epitope: C-terminus |
| Application【应用】 | Research Sub Category Apoptosis - Additional Anti-OCIAD1 Antibody detects level of OCIAD1 & has been published & validated for use in OCIAD1. Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blotting in HEK293 cell lysate. Western Blotting Analysis: 2 μg/mL of this antibody detected OCIAD1 in HEK293 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9NX40 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... OCIAD1(54940) |
产品说明
| Target description【目标描述】 | ~27 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
