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Anti-NMD3 antibody produced in rabbit
产品别名
Anti-NMD3 antibody produced in rabbit
Anti-CGI-07
Anti-NMD3 homolog (S. cerevisiae)
Anti-60S Ribosomal export protein NMD3
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | NMD3 ribosome export adaptor (NMD3) is an adaptor for 60S subunit export via the export receptor CRM1 (XPO1). In human, the C-terminal domain of NMD3 comprises a CRM1- dependent leucine-rich nuclear export signal (NES) and a nuclear localization signal (NLS) in its. Two zinc-binding centres and the ribosome-binding domain forms the N-terminal domain. |
| Immunogen【免疫原】 | peptide corresponding to an internal region of human NMD3, conjugated to KLH. The corresponding sequence is identical in mouse, rat, monkey, bovine and dog. |
| Application【应用】 | Anti-NMD3 antibody produced in rabbit has been used in immunoblotting and immunofluorescence. |
| Biochem/physiol Actions【生化/生理作用】 | NMD3 ribosome export adaptor (NMD3) is a highly conserved nucleocytoplasmic shuttling protein, essential for nuclear export of 60S ribosomal subunits. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~58 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1.0 mg/mL |
| technique(s) | indirect immunofluorescence: 2.5-5 μg/mL using human HeLa cells. western blot: 2.5-5.0 μg/mL using whole extracts of HEK-293T cells over-expressing mouse NMD3. |
| UniProt accession no.【UniProt登记号】 | Q96D46 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NMD3(51068) mouse ... Nmd3(97112) rat ... Nmd3(310512) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
