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Anti-LRP4 antibody produced in goat
产品编号: | 4109853 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-LRP4 antibody produced in goat
Anti-LRP10
Anti-KIAA0816
low density lipoprotein receptor-related protein 4
Anti-MEGF7
基本信息
NACRES | NA.41 |
General description【一般描述】 | Low density lipoprotein receptor-related protein 4 (LRP4) is expressed on the surface of the postsynaptic membranes. It acts as a receptor for agrin. The protein belongs to the low-density lipoprotein receptor-related proteins (LRPs) family. The LRP4 gene is localized on human chromosome 11p11.2. |
Immunogen【免疫原】 | Peptide with sequence CSNPSYRTSTQEVK , from the internal region of the protein sequence according to NP_002325.2. |
Biochem/physiol Actions【生化/生理作用】 | LRP4 (Low density lipoprotein receptor-related protein 4) is a multifunctional protein which controls the extracellular cell signaling pathways including Wnt β-catenin signaling. It is highly essential for maintaining the bone mineral density. LRP4 binds to Dkk1 (dickkopf 1) and sclerostin to control the bone growth via Wnt and bone morphogenic protein (BMP) signaling pathways. Clinically, it is highly important for the development of osteoporosis. Mutation in the LRP4 gene causes an autosomal-recessive congenital disorder, Cenani-Lenz syndrome characterized with limb and kidney malformations. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | indirect ELISA: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | O75096 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... LRP4(4038) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |