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Anti-LRP4 antibody produced in goat

产品编号:4109853
规格:affinity isolated antibody, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4109853100 μG5040
产品别名

Anti-LRP4 antibody produced in goat

Anti-LRP10

Anti-KIAA0816

low density lipoprotein receptor-related protein 4

Anti-MEGF7

基本信息
NACRES
NA.41
General description【一般描述】
Low density lipoprotein receptor-related protein 4 (LRP4) is expressed on the surface of the postsynaptic membranes. It acts as a receptor for agrin. The protein belongs to the low-density lipoprotein receptor-related proteins (LRPs) family. The LRP4 gene is localized on human chromosome 11p11.2.
Immunogen【免疫原】
Peptide with sequence CSNPSYRTSTQEVK , from the internal region of the protein sequence according to NP_002325.2.
Biochem/physiol Actions【生化/生理作用】
LRP4 (Low density lipoprotein receptor-related protein 4) is a multifunctional protein which controls the extracellular cell signaling pathways including Wnt β-catenin signaling. It is highly essential for maintaining the bone mineral density. LRP4 binds to Dkk1 (dickkopf 1) and sclerostin to control the bone growth via Wnt and bone morphogenic protein (BMP) signaling pathways. Clinically, it is highly important for the development of osteoporosis. Mutation in the LRP4 gene causes an autosomal-recessive congenital disorder, Cenani-Lenz syndrome characterized with limb and kidney malformations.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
goat
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: suitable
UniProt accession no.【UniProt登记号】
O75096
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... LRP4(4038)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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