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产品别名
Anti-LGN Antibody
G-protein-signaling modulator 2, Mosaic protein LGN, LGN
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | LGN is also known as G-protein-signaling modulator 2 (GPSM2). LGN has an important role in cellular structure and spindle pole orientation. LGN also stabilizes the apical complex during neuroblast divisions. LGN defects lead to Chudley-McCullough syndrome as well as a multiple micronuclei phenotype due to chromosomal mis-segregation and cell division errors. |
Specificity【特异性】 | Other Homologies: Human (85% sequence homology), Chicken (75% sequence homology). |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to mouse LGN. |
Application【应用】 | Research Category Cell Structure Anti-LGN Antibody is a highly specific rabbit polyclonal antibody, that targets LGN & has been tested in western blotting. Research Sub Category Cytoskeleton Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected LGN in mouse E16 brain tissue lysate. |
Quality【质量】 | Evaluated by Western Blotting in rat E16 heart tissue lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected LGN in rat E16 heart tissue lysate. |
Physical form【外形】 | Rabbit polyclonal serum with 0.05% sodium azide. Unpurified |
Analysis Note【分析说明】 | Control Heart tissue lysate |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | rat, mouse |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_083798 |
UniProt accession no.【UniProt登记号】 | Q8VDUO |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~77 kDa observed. Uncharacterized bands may be observed at ~30 kDa, ~60 kDa, and ~70 kDa in some cell lysates. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |