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Anti-LGI1 Antibody

产品编号:4109746
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4109746100 μG4740
产品别名

Anti-LGI1 Antibody

Leucine-rich glioma inactivated protein 1, Epitempin-1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Leucine-rich glioma inactivated gene 1 (LGI1), also known as Epitempin-1 (EPT), is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) regulating voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. LGI1 may play a role in the control of neuroblastoma cell survival and may play a role in other cancers. It is expressed in neural tissue, especially brain. Mutations in LGI1 have been associated with nearly half of autodominant lateral temporal epilepsy (ADTLE).
Specificity【特异性】
This antibody recognizes the N-terminus of LGI1.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to the N-terminus of human LGI1.
Application【应用】
Detect LGI1 using this rabbit polyclonal antibody, Anti-LGI1 Antibody validated for use in western blotting.
Quality【质量】
Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected LGI1 in 15 µg of mouse brain tissue lysate.
Other Notes【其他说明】
Antigen Affinity Purified
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse
species reactivity (predicted by homology)
human (immunogen homology)
technique(s)
western blot: suitable
UniProt accession no.【UniProt登记号】
O95970
shipped in【运输】
wet ice
Gene Information
human ... LGI1(9211)
产品说明
Target description【目标描述】
~56 kDa observed. Uniprot describes 3 isoforms at ~33 kDa, ~58 kDa, and ~64 kDa Uncharacterized bands may appear in some lysates.
【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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