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Anti-ITGAM antibody produced in goat

产品编号:4109370
规格:affinity isolated antibody, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4109370100 μG7060
产品别名

Anti-ITGAM antibody produced in goat

Anti-CD11B

Anti-Integrin

Anti-MAC-1

Anti-CR3A

Anti-α-M (complement component 3 receptor 3 subunit)

基本信息
MDL number
MFCD00240630
NACRES
NA.41
General description【一般描述】
Integrin α M (ITGAM) is also called as cluster of differentiation 11b (CD11b) or intercellular adhesion molecule-1 (ICAM-1). It is expressed on monocytes/macrophages, natural killer cells, neutrophils and a subset of B-and T-lymphocytes. ITGAM gene is located on human chromosome 16p11.
Immunogen【免疫原】
Peptide with sequence C-RNDGEDSYRTQ from the internal region of the protein sequence according to NP_000623.2 .
Biochem/physiol Actions【生化/生理作用】
Integrin α M (ITGAM) is involved in cell activation, chemotaxis, cytotoxicity and phagocytosis. It modulates the interaction of leukemic cells with microenvironment by binding inactivated complement component 3b (iC3b), intercellular adhesion molecule (ICAM), fibrinogen, beta-glukanes, coagulation factor X etc. ITGAM is considered as a marker for myeloid-derived suppressor cells that participates in restraining antitumor immunity of the host and inducing the enlargement and drug-resistance of hematological malignant cells. D11b integrin contributes to ICAM-1-dependent AIDP patient mononuclear leukocyte adhesion.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
goat
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
UniProt accession no.【UniProt登记号】
P11215
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ITGAM(3684)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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