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Anti-Integrin beta7 Antibody, clone TN114
产品别名
Anti-Integrin beta7 Antibody, clone TN114
integrin, beta 7, integrin beta 7 subunit, Gut homing receptor beta subunit
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, α4β7, is specifically involved in the homing and migration of lymphocytes to the gut, while αEβ7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGFβ1. Integrin beta7 has been observed in several different leukocyte lines. |
| Specificity【特异性】 | The antibody recognizes Integrin beta7. |
| Immunogen【免疫原】 | Epitope: Unknown Purified human integrin beta7 protein. |
| Application【应用】 | Research Category Cell Structure Research Sub Category Integrins Anti-Integrin beta7 Antibody, clone TN114 is an antibody against Integrin beta7 for use in FC, IP, IH. |
| Quality【质量】 | Evaluated by Flow Cytometry in human PBMC′s. Flow Cytometry Analysis: 1 µg/mL of this antibody detected Integrin beta7 on human PBMC′s. |
| Physical form【外形】 | Purified armenian hamster monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Human peripheral blood mononuclear cells (PBMC′s). |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | hamster (Armenian) |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | TN114, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NP_000880.1 |
| UniProt accession no.【UniProt登记号】 | P26010 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 86 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
