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Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free)
产品别名
Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free)
Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, Integrin alpha-V heavy chain, Integrin alpha-V light chain, Intergrin av
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Integrin alpha-V (or CD51; vitronectin receptor subunit alpha) protein is a transmembrane receptor that mediates adhesion of cells to each other and to the extracellular matrix. Integrin receptors are activated by a variety of intracellular signals that modify its cytoplasmic domain and induce configural changes in integrin molecules thereby enabling ligand binding to the extracellular surface. An important part of this process is the binding of the actin protein, talin, to the integrin cytoplasmic domain. |
| Immunogen【免疫原】 | Human Placental ɑvβ3 |
| Application【应用】 | Research Category Cell Structure Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free) detects level of Integrin alpha-V & has been published & validated for use in Flow Cytometry, Immunoprecipitation, Activity Assay. Immunoprecipitation Analysis: A representative lot was used by an independent laboratory to detect Integrin alpha-V in M21 cell lysates. (Mitjans, F., et al (1995). Journal of Cell Science. 108:2825-2838.) Research Sub Category Adhesion (CAMs) |
| Quality【质量】 | Evaluated by Flow Cytometry in HeLa cells. Flow Cytometry Analysis: 0.5 µg of this antibody detected Integrin alpha-V in HeLa cells. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing PBS without preservative. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control HeLa cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 272-17E6, monoclonal |
| species reactivity | human |
| technique(s) | activity assay: suitable flow cytometry: suitable immunoprecipitation (IP): suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001138472 |
| UniProt accession no.【UniProt登记号】 | P06756 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ITGAV(3685) |
产品说明
| Target description【目标描述】 | 116 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
