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Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate
| 产品编号： | 4109052 |
| 规格： | clone 20A12.1, from mouse, ALEXA FLUOR® 647 |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate
Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.45 |
| General description【一般描述】 | Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis. |
| Application【应用】 | Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence. The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications. |
| Quality【质量】 | Evaluated by Immunofluorescence in human spleen tissue. Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue. |
| Other Notes【其他说明】 | Protein G Purified |
| Legal Information【法律信息】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | ALEXA FLUOR® 647 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 20A12.1, monoclonal |
| species reactivity | rat, mouse, human |
| technique(s) | immunofluorescence: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001614 |
| UniProt accession no.【UniProt登记号】 | P55008 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... AIF1(199) |
产品说明
| Target description【目标描述】 | ~17 kDa observed. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
