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Anti-Human IgG3 antibody, Mouse monoclonal
产品编号: | 4109004 |
规格: | clone HP-6050, purified from hybridoma cell culture |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Human IgG3 antibody, Mouse monoclonal
Anti-Immunoglobulin G3
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified from hybridoma cell culture |
antibody product type | primary antibodies |
clone【克隆】 | HP-6050, monoclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
concentration【浓度】 | ~1.0 mg/mL |
technique(s) | immunoprecipitation (IP): 1-2.5 μg/test using Human IgG3 myeloma indirect ELISA: 0.15-0.3 μg/mL using 1 μg/ml Human IgG3 myeloma for coating |
isotype【同位素/亚型】 | IgG1 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
基本信息
General description【一般描述】 | Human IgG consist of four subclasses (1-4) that can be recognized by antigenic differences in their heavy chains. They constitute approximately 65, 30, 5 and 4% of the total IgG, respectively. The abundance of the different IgG subclasses in the bloodstream varies with age, IgG1 and IgG3 reach normal adult levels by 5-7 years of age while IgG2 and IgG4 levels rise more slowly, reaching adult levels at about 10 years of age. |
Immunogen【免疫原】 | Human IgG3 myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads |
Application【应用】 | Anti-Human IgG3 antibody, mouse monoclonal has been used in indirect ELISA and immunoprecipitation. |
Biochem/physiol Actions【生化/生理作用】 | IgG1 and IgG3 are the only subclasses capable of adherence to mononuclear phagocytes and are recognized readily by the Fc receptors on various reticulo-endothelial . IgG3 deficiency has been associated with a history of recurrent infectious, leading to chronic lung disease. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |