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Anti-Human IgG3 antibody, Mouse monoclonal

产品编号:4109004
规格:clone HP-6050, purified from hybridoma cell culture
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4109004100 μL7630
产品别名

Anti-Human IgG3 antibody, Mouse monoclonal

Anti-Immunoglobulin G3

产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
antibody form【抗体形式】
purified from hybridoma cell culture
antibody product type
primary antibodies
clone【克隆】
HP-6050, monoclonal
form【形式】
buffered aqueous solution
species reactivity
human
concentration【浓度】
~1.0 mg/mL
technique(s)
immunoprecipitation (IP): 1-2.5 μg/test using Human IgG3 myeloma
indirect ELISA: 0.15-0.3 μg/mL using 1 μg/ml Human IgG3 myeloma for coating
isotype【同位素/亚型】
IgG1
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
基本信息
General description【一般描述】
Human IgG consist of four subclasses (1-4) that can be recognized by antigenic differences in their heavy chains. They constitute approximately 65, 30, 5 and 4% of the total IgG, respectively. The abundance of the different IgG subclasses in the bloodstream varies with age, IgG1 and IgG3 reach normal adult levels by 5-7 years of age while IgG2 and IgG4 levels rise more slowly, reaching adult levels at about 10 years of age.
Immunogen【免疫原】
Human IgG3 myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads
Application【应用】
Anti-Human IgG3 antibody, mouse monoclonal has been used in indirect ELISA and immunoprecipitation.
Biochem/physiol Actions【生化/生理作用】
IgG1 and IgG3 are the only subclasses capable of adherence to mononuclear phagocytes and are recognized readily by the Fc receptors on various reticulo-endothelial . IgG3 deficiency has been associated with a history of recurrent infectious, leading to chronic lung disease.
Physical form【外形】
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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