Anti-Histone H3.3 Antibody, clone 6C4A3

32160702

NA.41

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Western Blotting Analysis: 0.1 µg/mL from a representative lot detected Histone H3.3 with recombinant H3.3 proteins. Additionally, 1 µg/mL from a representative lot detected Histone H3.3 in HeLa, COS1, NIH/3T3, NRK, and MDCK whole cell lysates (Prof. Taro Tachibana, Cell Engineering Corporation.).
Anti-Histone H3.3 Antibody, clone 6C4A3 is an antibody against Histone H3.3 for use in western blotting.

Evaluated by Western Blotting in HeLa acid extract.

Western Blotting Analysis: 1 µg/mL of this antibody detected Histone H3.3 in 10 µg of HeLa acid extract.

Protein G Purified
Format: Purified

100

rat

purified immunoglobulin

primary antibodies

6C4A3, monoclonal

canine, monkey, mouse, human

1 mg/mL

western blot: suitable

IgG2aκ

NP_002098

P84243

wet ice

human ... H3F3B(3021)

~17 kDa observed

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12 - Non Combustible Liquids

WGK 1