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Anti-Granzyme B Antibody, clone GrB-7

产品编号:4108408
规格:culture supernatant, clone GrB-7, Chemicon®
包装规格:250 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4108408250 μL5850
基本信息
eCl@ss
32160702
NACRES
NA.41
Specificity【特异性】
Monoclonal antibody recognizes the 33 kDa granzyme B.

Reacts specifically with human serine protease granzyme B. Does not cross-react with human granzyme A. Granzyme B localizes in cytoplasmic granules and can be used as a marker for NK cells and activated cytotoxic T-cells.
Application【应用】
Detect Granzyme B using this Anti-Granzyme B Antibody, clone GrB-7 validated for use in WB, IH(P).
Research Sub Category
Apoptosis - Additional

Enzymes & Biochemistry
Immunoblotting

Immunohistochemistry of granzyme B-expressing lymphocytes in sublimate sections and formalin-fixed paraffin-embedded tissues (1:20 dilution). Does not react with other cell types. Cannot be used on frozen sections.

Note on the use of MAB3070 on paraffin sections:

Tissue slides should be pretreated with an antigen retrieval method, such as treatment with 0.1M sodium citrate for 10 min at 100°C. A working dilution of 1:20 is advised, but optimal working dilutions must be determined by end user.
Research Category
Apoptosis & Cancer

Metabolism
Physical form【外形】
Liquid
Legal Information【法律信息】
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
culture supernatant
antibody product type
primary antibodies
clone【克隆】
GrB-7, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype【同位素/亚型】
IgG2a
NCBI accession no.【NCBI登记号】
NM_004131.3
UniProt accession no.【UniProt登记号】
P10144
shipped in【运输】
dry ice
Gene Information
human ... GZMB(3002)
产品说明
Storage and Stability【储存及稳定性】
Maintain at -20°C for up to 12 months.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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