Anti-GOT2 (AA 295-306) antibody produced in goat

NA.41

The GOT2 (glutamic-oxaloacetic transaminase 2) gene is mapped to human chromosome 16q21 and the encoded protein is localized to mitochondria.

Peptide with sequence CKDADEAKRVES from the internal region of the protein sequence according to NP_002071.2.

GOT2 (glutamic-oxaloacetic transaminase 2) participates in malate–aspartate shuttle, which increases the rate of glycolysis via cytosolic NADH (nicotinamide adenine dinucleotide) transfer into mitochondria. This supports rapid growth in tumor cell. GOT2 catalyzes the transamination reaction involving oxaloacetate and L-glutamate to give rise to aspartate, also generating α-ketoglutarate in mitochondria. Aspartate, that is formed, serves as a precursor of N-acetylaspartate, a predominantly abundant free amino acid found in the brain.

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

100

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

rat, human, mouse

indirect ELISA: suitable
western blot: suitable

P00505

dry ice

−20℃

human ... GOT2(2806)

GHS07

Warning

H315 - H319

P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2

12 - Non Combustible Liquids

WGK 2