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Anti-Glutamate Receptor 3 Antibody, clone 3B3
产品别名
Anti-Glutamate Receptor 3 Antibody, clone 3B3
AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD. |
| Specificity【特异性】 | Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2. |
| Immunogen【免疫原】 | Fusion protein, N-terminus of GluR3 |
| Application【应用】 | Immunohistochemistry: A previous lot of this antibody was used in IH. Optimal working dilutions must be determined by end user. Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P). |
| Quality【质量】 | Western Blot Analysis: A previous lot of this antibody was used in WB. |
| Physical form【外形】 | Liquid in PBS. Contains no preservative. Format: Purified Protein A purified |
| Analysis Note【分析说明】 | Control Brain Hippocampal tissue |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 3B3, monoclonal |
| species reactivity | monkey, mouse, human |
| species reactivity (predicted by homology) | rat |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NM_000840.2 |
| UniProt accession no.【UniProt登记号】 | P42263 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... GRIA3(2892) |
产品说明
| Target description【目标描述】 | ~ 110 kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
