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Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17
产品别名
Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17
GABA(A) receptor subunit beta-2, gamma-aminobutyric acid (GABA) A receptor, beta 2, gamma-aminobutyric acid A receptor, beta 2
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines. |
Specificity【特异性】 | Reacts with the β-chain of the GABAA receptor. |
Immunogen【免疫原】 | Purified GABA/benzodiazepine receptor from bovine cortex Epitope: Extracellular domain of the beta2 & beta3 subunits of the GABAA receptor |
Application【应用】 | Immunohistochemistry: A 10-20 μg/mL concetration of a previous lot was used in IH. Immunoprecipitation: A previous lot of this antibody was used in IP. Western blot: 5-20 µg/mL. Recognizes a 55 kDa band corresponding to the beta chain of the GABAA receptor. Optimal working dilutions must be determined by end user. Detect GABA A Receptor β 2 using this Anti-GABA A Receptor β 2, 3 Chain Antibody, clone BD17 validated for use in IH, IP & WB. |
Quality【质量】 | Evaluated by Western Blot on mouse brain membrane lysates. Western Blot: 1:500 dilution of this antibody detected GABA A Receptor β 2,3 Chain on 10 μg of mouse brain membrane lysates. |
Linkage【联系】 | Replaces: AB5952 |
Physical form【外形】 | Format: Purified Protein A purified Purified mouse monoclonal IgG1 liquid in buffer containing 10 mM potassium phosphate buffer pH 7.4 with 150 mM NaCl |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | BD17, monoclonal |
species reactivity | monkey, mouse, feline, bovine |
species reactivity (predicted by homology) | human, rat |
manufacturer/tradename | Chemicon® |
technique(s) | immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1 |
NCBI accession no.【NCBI登记号】 | NM_000813.2 |
UniProt accession no.【UniProt登记号】 | P47870 |
shipped in【运输】 | dry ice |
Gene Information | human ... GABRB2(2561) |
产品说明
Target description【目标描述】 | 55 kDa |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |