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Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17

产品编号:4108010
规格:clone BD17, Chemicon®, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4108010100 μG7700
产品别名

Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17

GABA(A) receptor subunit beta-2, gamma-aminobutyric acid (GABA) A receptor, beta 2, gamma-aminobutyric acid A receptor, beta 2

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines.
Specificity【特异性】
Reacts with the β-chain of the GABAA receptor.
Immunogen【免疫原】
Purified GABA/benzodiazepine receptor from bovine cortex
Epitope: Extracellular domain of the beta2 & beta3 subunits of the GABAA receptor
Application【应用】
Immunohistochemistry:
A 10-20 μg/mL concetration of a previous lot was used in IH.

Immunoprecipitation:
A previous lot of this antibody was used in IP.

Western blot:
5-20 µg/mL. Recognizes a 55 kDa band corresponding to the beta chain of the GABAA receptor.

Optimal working dilutions must be determined by end user.
Detect GABA A Receptor β 2 using this Anti-GABA A Receptor β 2, 3 Chain Antibody, clone BD17 validated for use in IH, IP & WB.
Quality【质量】
Evaluated by Western Blot on mouse brain membrane lysates.

Western Blot:
1:500 dilution of this antibody detected GABA A Receptor β 2,3 Chain on 10 μg of mouse brain membrane lysates.
Linkage【联系】
Replaces: AB5952
Physical form【外形】
Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 liquid in buffer containing 10 mM potassium phosphate buffer pH 7.4 with 150 mM NaCl
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information【法律信息】
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
BD17, monoclonal
species reactivity
monkey, mouse, feline, bovine
species reactivity (predicted by homology)
human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype【同位素/亚型】
IgG1
NCBI accession no.【NCBI登记号】
NM_000813.2
UniProt accession no.【UniProt登记号】
P47870
shipped in【运输】
dry ice
Gene Information
human ... GABRB2(2561)
产品说明
Target description【目标描述】
55 kDa
【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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