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Anti-FucT-III Antibody

产品编号:4107978
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4107978100 μG6020
产品别名

Anti-FucT-III Antibody

Galactoside 3(4)-L-Fucosyltransferase, Blood Group Lewis Alpha-4-Fucosyltransferase, Lewis Ft, Fucosyltransferase 3, Fucosyltransferase Iii, Fuct-Iii, Alpha-(1,3)-Fucosyltransferase 3

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Alpha-(1,3)-fucosyltransferase 3 (FucT-III; Galactoside 3(4)-L-fucosyltransferase) is highly expressed in the small intestine, colon, stomach, and kidney. It is a member of the glycosyltransferase family of proteins which are involved in a glycosylation pathway that attaches fucose to Lewis epitopes of target molecules. This type of post-translational modification allows modified (fucosylated) molecules to recognize specific target substrates. Fucosyltransferases may therefore play an important role in communication at the cell surface. FucT-III may play a role in blood group determination as it is involved in the expression of antigens such as Lewis B, sialy Lewis X, Vim-2, and Lewis A.
Specificity【特异性】
This antibody recognizes FucT-III at the lumenal region.
No homology to Rat and Mouse was found.
Immunogen【免疫原】
Epitope: Lumenal region
KLH-conjugated linear peptide corresponding to the lumenal region of human FucT-III.
Application【应用】
Research Category
Cell Structure
Research Sub Category
Glycobiology
Anti-FucT-III Antibody detects level of FucT-III & has been published & validated for use in Western Blotting.
Western Blot Analysis: 1 µg/mL from a representative lot detected FucT-III on 10 µg of transfected lysate and did not detect the non transfected lysate.
Quality【质量】
Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected FucT-III on 10 µg of human liver tissue lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
Analysis Note【分析说明】
Control
Human Liver Tissue Lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
chimpanzee (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
Np_000140
UniProt accession no.【UniProt登记号】
P21217
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
~50 kDa observed. The calculated molecular weight of this protein is 42 kDa, but can be observed at ~50 kDa due to high glycosylation. (Christensen, L, et al. (2000). Glycobiology. 10(9):931-939.)
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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