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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | monoclonal |
form【形式】 | liquid |
species reactivity | mouse, human |
concentration【浓度】 | 0.4 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | Q99714 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HSD17B10(3028) |
基本信息
General description【一般描述】 | This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014] |
Immunogen【免疫原】 | A synthesized peptide derived from human ERAB/HSD17B10 |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |