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Anti-DPAGT1 Antibody

产品编号:4107184
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4107184100 μG6020
产品别名

Anti-DPAGT1 Antibody

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, also known as GlcNAc-1-P transferase (G1PT or GPT) or N-acetylglucosamine-1-phosphate transferase, and encoded by the gene name DPAGT1 or DPAGT2, is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.
Immunogen【免疫原】
KLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
Epitope: N-terminus
Application【应用】
Research Category
Signaling
Anti-DPAGT1 Antibody detects level of DPAGT1 & has been published & validated for use in DPAGT1.
Research Sub Category
Developmental Signaling
Quality【质量】
Evaluated by Western Blotting in mouse kidney tissue lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected DPAGT1 in mouse kidney tissue lysate with and without blocking peptide.
Physical form【外形】
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse
technique(s)
western blot: suitable
UniProt accession no.【UniProt登记号】
Q9H3H5
shipped in【运输】
wet ice
Gene Information
human ... DPAGT1(1798)
产品说明
Target description【目标描述】
~42 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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