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Anti-Dopamine β Hydroxylase-SAP Antibody, clone 4F10.2

产品编号:4107170
规格:clone 4F10.2, Chemicon®, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4107170100 μG24630
基本信息
eCl@ss
32160702
NACRES
NA.41
Specificity【特异性】
Dopamine b-HydroxylaseDBH is a single gene product that exists as a cytosolic enzyme, as a membrane protein and is secreted into the circulation (Lewis & Asnani, 1992). Because of its residence time as a plasma membrane-bound protein, it is able to be used as a targeting agent for neurons. The target neurons include postganglionic sympathetic neurons and all noradrenergic and adrenergic neurons of the central nervous system. As such anti-DBH-SAP can be used for the production of acute peripheral autonomic failure in a model for the human disease. It can also be used for the analysis of the behavioral effects of noradrenergic or adrenergic ablation. When injected intraventricularly, noradrenergic neurons of the locus coeruleus are eliminated (Wiley & Lappi, 1994). The antibody and immunotoxin undergo retrograde transport.

MAB308 is the unconjugated monoclonal.
Application【应用】
Immunotoxin
Research Category
Neuroscience
Detect Dopamine β Hydroxylase using this Anti-Dopamine β Hydroxylase-SAP Antibody, clone 4F10.2 validated for use in 0.
Research Sub Category
Neurodegenerative Diseases
Physical form【外形】
Saporin Conjugated. Sterile liquid. Provided in phosphate buffered saline. Contains no preservative.
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information【法律信息】
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
saporin
antibody product type
primary antibodies
clone【克隆】
4F10.2, monoclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunolesioning: suitable
isotype【同位素/亚型】
IgG1
NCBI accession no.【NCBI登记号】
NM_000787.3
UniProt accession no.【UniProt登记号】
P09172
shipped in【运输】
dry ice
产品说明
Storage and Stability【储存及稳定性】
The material should be stored at -80°C for up to six months under sterile conditions. Avoid repeated freeze-thaw cycles.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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