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产品别名
Anti-COX antibody produced in rabbit
COX IV-1
COXIV
COX4
COXIV-1
COX4-1
COX IV
COX4I1
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 19 |
species reactivity | mouse, rat, human |
concentration【浓度】 | 2.04 mg/ml |
technique(s) | immunofluorescence: 1:50-1:200 immunohistochemistry: 1:50-1:200 immunoprecipitation (IP): 1:50-1:100 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P13073 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... COX4I1(1327) |
基本信息
General description【一般描述】 | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3′ of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen【免疫原】 | Recombinant fusion protein containing a sequence corresponding to amino acids 23-169 of human COX IV (NP_001852.1). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |