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Anti-Cortactin antibody produced in rabbit

产品编号:4106585
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41065854660
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
monoclonal
form【形式】
liquid
species reactivity
mouse, rat, human
concentration【浓度】
0.21 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
Q14247
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CTTN(2017)
基本信息
General description【一般描述】
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Immunogen【免疫原】
A synthesized peptide derived from human Cortactin
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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