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Anti-CLEC2A Antibody
| 产品编号： | 4106317 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CLEC2A Antibody
C-type lectin domain family 2 member A, Keratinocyte-associated C-type lectin, KACL, Proliferation-induced lymphocyte-associated receptor, PILAR, UNQ579, PRO19597
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | C-type lectin domain family 2 member A (CLEC2A) is also called proliferation-induced lymphocyte-associated receptor (PILAR) and Keratinocyte-associated C-type lectin (KACL). CLEC2A is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Modulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer. CLEC2A is associated with expansion of TCR-stimulated T-cells, modulates the capacity of T-cells to home to lymph nodes through SELL, and facilitates immune recognition of keratinocytes by stimulating natural killer cell mediated cytotoxicity. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human CLEC2A. |
| Application【应用】 | Research Sub Category Apoptosis - Additional Anti-CLEC2A Antibody is a highly specific rabbit polyclonal antibody, that targets CLEC2A & has been tested in western blotting. Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blotting/Peptide Inhibition Assay in K562 cell lysate. Western Blotting/Peptide Inhibition Analysis: 1 µg/mL of this antibody detected CLEC2A in 15 µg of K562 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control K562 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q6UVW9 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~32 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~19 kDa and ~20 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
