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Anti-Claudin-11 Antibody
产品编号: | 4106306 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Claudin-11 Antibody
Claudin-11, Oligodendrocyte-specific protein
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis. |
Specificity【特异性】 | This antibody recognizes the cytoplasmic domain of Claudin-11. Other homologies: Mouse and Rat (93% sequence homology). |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11. Epitope: Cytoplasmic domain |
Application【应用】 | Research Category Cell Structure Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate. Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate. Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting. Research Sub Category ECM Proteins |
Quality【质量】 | Evaluated by Western Blot in human brain tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
Analysis Note【分析说明】 | Control Human brain tissue lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology) |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_005593 |
UniProt accession no.【UniProt登记号】 | O75508 |
shipped in【运输】 | wet ice |
Gene Information | human ... CLDN11(5010) |
产品说明
Target description【目标描述】 | ~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |