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Anti-CKAP5 Antibody
| 产品编号： | 4106294 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CKAP5 Antibody
Cytoskeleton-associated protein 5, Colonic and hepatic tumor over-expressed gene protein, Ch-TOG
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Cytoskeleton-associated protein 5 (CKAP5) is a member of the TOG/XMAP215 family containing heat repeats and plays a role in kinetochore mircotubule protection from depolymerization by MCAK. CKAP5 is the homolog of the Xenopus protein, XMAP25 (also known as chTog), which plays an essential role in centrosomal assembly. CKAP5 is localized in the perinuclear cytoplasm during interphase and at the spindle poles and centrosomes during mitosis. Studies show CKAP5 interacts with TACC1, TACC3, and tubulin leading to the hypothesis that it functions in spindle microtuble organization. Hepatomas and colonic tumors have shown overexpression of CKAP5. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human CKAP5. |
| Application【应用】 | Research Category Cell Structure Immunocytochemistry Analysis: A 1:250 dilution from a previous lot detected CKAP5 in RPE1 cells. Research Sub Category Cytoskeleton Anti-CKAP5 Antibody is an antibody against CKAP5 for use in IC. |
| Quality【质量】 | Evaluated by Immunocytochemistry in A431 cells. Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected CKAP5 in A431 cells. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control A431 cells |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| species reactivity (predicted by homology) | rat (based on 100% sequence homology), mouse (based on 100% sequence homology), canine (based on 100% sequence homology), bovine (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001008938 |
| UniProt accession no.【UniProt登记号】 | Q14008 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... CKAP5(9793) |
产品说明
| Target description【目标描述】 | 226 kDa calculated. Three isoforms are produced by alternative splicing with molecular weights of 225, 218, and 226 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
