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Anti-BCAR3 Antibody

产品编号:4105328
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4105328100 μG5850
产品别名

Anti-BCAR3 Antibody

Breast cancer anti-estrogen resistance 3, NSP2, SH2D3B, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to human BCAR3.
Application【应用】
Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.
Research Category
Apoptosis & Cancer
Quality【质量】
Evaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
Analysis Note【分析说明】
Control
Mouse kidney tissue lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
mouse
species reactivity (predicted by homology)
human (immunogen homology)
technique(s)
western blot: suitable
UniProt accession no.【UniProt登记号】
O75815
shipped in【运输】
wet ice
Gene Information
human ... BCAR3(8412)
产品说明
Target description【目标描述】
~104 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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