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Anti-ATG5 Antibody, clone 177.19
产品别名
Anti-ATG5 Antibody, clone 177.19
APG5 autophagy 5-like, APG5 autophagy 5-like (S. cerevisiae), APG5 (autophagy 5, S. cerevisiae)-like, ATG5 autophagy related 5 homolog (S. cerevisiae), ATG5 autophagy related 5-like, Apoptosis-specific protein
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity |
| Specificity【特异性】 | The antibody reacts with the 50 kDa ATG5 protein. Other species have not been tested. |
| Immunogen【免疫原】 | Linear Peptide, aa: 8-318 |
| Application【应用】 | Research Sub Category Apoptosis - Additional This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5. Immunoprecipitation: HeLa cell lysate Research Category Apoptosis & Cancer |
| Quality【质量】 | Western Blot Analysis: 0.5 ug/mL of this antibody detected ATG5 on HeLa cell lysate. |
| Linkage【联系】 | Replaces: MABC137 |
| Physical form【外形】 | Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Western Blot and Immunoprecipitation: HeLa cell lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 177.19, monoclonal |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2bκ |
| NCBI accession no.【NCBI登记号】 | NM_004849.2 |
| UniProt accession no.【UniProt登记号】 | Q9H1Y0 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 50 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
