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Anti-ARX Antibody, clone 11F6.2
产品别名
Anti-ARX Antibody, clone 11F6.2
Homeobox protein ARX, Aristaless-related homeobox
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Aristaless-related homeobox protein (ARX) is a transcription factor that plays an important role in the development of the brain, testis, and pancreas. The gene targets and nuclear associations of ARX are less clear, although it has been demonstrated that ARX interacts with the Pax4 promoter. However, over fifty ARX mutations have been identified and the resultant phenotypes have been well studied. ARX mutations are X-linked and lead to various syndromes including X-linked West syndrome; X-linked myoclonic epilepsy; Partington syndrome; and X-linked mental retardation. |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human ARX. |
Application【应用】 | Immunohistochemistry Analysis: A 1:1,000 dilution from a reprsentative lot detected ARX in human brain tissue. Research Category Neuroscience Research Sub Category Developmental Neuroscience Detect ARX using this Anti-ARX Antibody, clone 11F6.2 validated for use in Western Blotting, IHC(P). |
Quality【质量】 | Evaluated by Western Blot in human pancreas tissue lysate. Western Blot Analysis: 2 µg/mL of this antibody detected ARX in 200 µg of human pancreas tissue lysate. |
Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
Analysis Note【分析说明】 | Control Human pancreas tissue lysate. |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 11F6.2, monoclonal |
species reactivity | human |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_620689 |
UniProt accession no.【UniProt登记号】 | Q96QS3 |
shipped in【运输】 | wet ice |
Gene Information | human ... ARX(170302) |
产品说明
Target description【目标描述】 | ~58 kDa observed. An uncharacterized band may be observed at ~23 kDa in some tissue lysates. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |