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Anti-ADNP1 Antibody, clone 5F5.1

产品编号:4104653
规格:clone 5F5.1, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4104653100 μG5520
基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
ADNP1, also known as Activity-dependent neuroprotector homeobox protein, and encoded by the gene ADNP/ADNP1/KIAA0784, is a potential transcription factor that appears to mediate some of the neuroprotective peptide VIP associated effects involving normal growth and cancer proliferation. ADNP1 is widely expressed and localized to the nucleus. ADNP1 is strongly expressed in heart and skeletal muscle tissue and the brain. ADNP1 is also found expressed in colon and breast cancer tissues but not in normal tissues, thus ADNP1 can be used as a potential cancer marker in some tissues. ADNP1 is upregulated in normal proliferative tissues by VIP, and it may increase the viability of certain cell types through the modulation of p53 activity. Interestingly, new research shows that ADNP1 may be a potential biomarker for Alzheimer’s disease, where ADP1 expression was specifically down-regulated in AD patients.
Immunogen【免疫原】
Epitope: Near C-terminus
GST-tagged recombinant protein corresponding to human ADNP1, near the C-terminus.
Application【应用】
This Anti-ADNP1 Antibody, clone 5F5.1 is validated for use in Western Blotting for the detection of ADNP1.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
Quality【质量】
Evaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected ADNP1 in 200 µg of SH-SY-5Y cell lysate.
Physical form【外形】
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
Other Notes【其他说明】
Concentration: Please refer to lot specific datasheet.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
5F5.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype【同位素/亚型】
IgG1κ
NCBI accession no.【NCBI登记号】
NP_056154
UniProt accession no.【UniProt登记号】
Q9H2P0
shipped in【运输】
wet ice
Gene Information
human ... ADNP(23394)
产品说明
Target description【目标描述】
~145 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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