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Anti- HP1 alpha/CBX5 antibody produced in rabbit

产品编号:4104270
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41042704660
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
concentration【浓度】
7.94 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P45973
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CBX5(23468)
基本信息
General description【一般描述】
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen【免疫原】
Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human HP1 alpha/HP1 alpha/CBX5 (NP_001120794.1).
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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