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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | liquid |
species reactivity | mouse, human, rat |
concentration【浓度】 | 0.52 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P09429 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HMGB1(3146) |
基本信息
General description【一般描述】 | This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. |
Immunogen【免疫原】 | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HMGB1 (NP_002119.1). |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |