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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | monoclonal |
form【形式】 | liquid |
species reactivity | human, mouse, rat |
concentration【浓度】 | 0.28 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | Q13547 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... HDAC1(3065) |
基本信息
General description【一般描述】 | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] |
Immunogen【免疫原】 | A synthesized peptide derived from human HDAC1. |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |