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产品别名
Anti-ERK2 antibody produced in rabbit
PRKM2
ERK2
p38
p41mapk
ERK-2
MAPK2
MAPK1
p40
P42MAPK
p41
ERT1
p42-MAPK
ERK
PRKM1
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 36 kDa 41 |
species reactivity | mouse, rat, human |
concentration【浓度】 | 0.9 mg/ml |
technique(s) | immunohistochemistry: 1:50-1:100 western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P28482 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MAPK1(5594) |
基本信息
General description【一般描述】 | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Immunogen【免疫原】 | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_620407.1). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |