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Anti- CDKN1B/p27KIP1 antibody produced in rabbit

产品编号:4104214
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41042144660
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
mouse, rat, human
concentration【浓度】
2.75 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P46527
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... CDKN1B(1027)
基本信息
General description【一般描述】
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
Immunogen【免疫原】
Recombinant protein of human CDKN1B/p27KIP1
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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